After an impressive 31-10 win over the Cowboys, faith is building back in the Bills. The Bills are another team hitting their stride at the right moment. Point Spread Bet: Los Angeles Rams -4 (-115).To open Week 16 on Thursday Night Football, consider backing the Rams to win and cover the spread. New Orleans was one of our best NFL bets of Week 15, but this is a much tougher task on the road. The Rams will welcome a Saints squad coming off a confidence-building 24-6 win over the Giants. They’ve won four of their last four games, with their only loss in OT against the Ravens, 37-31. The Rams are one of the hottest teams in the NFL. All Week 16 NFL odds are courtesy of Bovada: New Orleans Saints vs. There are multiple playoff spots to fill and the majority of teams are still mathematically alive for the postseason.Īfter going through the entire card, we are making our best Week 16 NFL predictions and parlay. As the 2023-24 NFL regular season heads into the final three weeks of action, we are dissecting the latest NFL Week 16 odds at NFL betting sites.Īt this point of the year, there isn’t much room for error down the stretch.